Synthesis techniques, characterization and mechanical properties of natural derived hydroxyapatite scaffolds for bone implants: a review

نویسندگان

چکیده

Abstract Hydroxyapatite (HAp) with good mechanical properties is a promising material meant for number of useful bids in dentistry and orthopedic biomedical engineering applications drug delivery, bone defect fillers, cements, etc. In this paper, comprehensive review has been done, by reviewing different literatures related to synthesis techniques, property testing, method calcination characterization hydroxyapatite which are product catfish bovine bones. The discussion relations the obligatory features vital attain best envisioned bid graft. process approaches that capable fabricating essential microstructure ways advance natural mined HAp reviewed. standard values tensile strength were found be within range 40–300 MPa, compressive was 400–900 while Elastic modulus 80–120 GPa fracture toughness 0.6–1 MPa m 1/2 (Ramesh et al. Ceram Int 44(9):10525–10530, 2018; Landi J Eur Soc 20(14–15):2377–2387, 2000; Munar Dent Mater 25(1):51–58, 2006). Also, porosity 70–85% (Yang Am Bull 89(2):24–32, 2010), density 3.16 g/cm 3 relative 95–99.5% literature revealed CaP ratio varies relation source sintering temperature. For example, bone, 1.7 (Mezahi Therm Anal Calorim 95(1):21–29, 2009) 1.65 (Barakat Process Technol 209(7):3408–3415, obtained at 1100 °C 750 respectively. Basic understanding on effect adding foreign as strengthening agent ground factor development new biomaterial (Natural hydroxyapatite, NHAp). Therefore, it inferred upon careful combination main parameters such compaction pressures, temperatures, dwell times production (NHAp), can enhanced. Graphic abstract

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ژورنال

عنوان ژورنال: SN applied sciences

سال: 2021

ISSN: ['2523-3971', '2523-3963']

DOI: https://doi.org/10.1007/s42452-021-04795-y